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Physicians can use T3 instead of levothyroxine (T4) for patients undergoing thyroid withdrawal. When a patient has thyroid cancer or Grave s, I-131 ablation therapy can be used to remove any trace thyroid tissue. In order for I-131 therapy to be effective, the trace thyroid tissue must be avid to iodine. The best method is to starve the tissue of iodine but this can lead to hypothyroid symptoms for the patient. Withdrawal from levothyroxine can be done but it takes 6 weeks of withdrawal for the remaining thyroid tissue to be completely starved. 6 weeks is needed owing to levothyroxine s long half life. 6 weeks can be inconvenient for the patient and delay treatment. Liothyronine (T3) instead can be taken and withdrawn from for 2 weeks to starve the thyroid tissue. This is much safer and more convenient than levothyroxine.
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